these plant-derived psychoactive chemicals share an affinity for a receptor
Agen Bandar Togel Online Terpercaya About one in every hundred people has epilepsy. Epileptic seizures can be described as an electrical storm in the brain. These storms typically begin at a single spot where nerve cells begin repeatedly firing together in synchrony. The hyperactivity often spreads from that one spot to other areas throughout the brain, causing symptoms such as loss of consciousness and convulsions. It’s typical for the person experiencing a seizure to need tens of minutes before becoming clearheaded again.
agenangka The majority of epileptic seizures originate in the hippocampus, a brain structure buried in the temporal lobe, says Ivan Soltesz, co-senior author of the study and professor of neurosurgery at Stanford University School of Medicine.
Agen Bandar Togel Online Terpercaya The hippocampus plays an outsized role in short-term memory, learning, and spatial orientation. Its ability to quickly adopt new neuronal firing patterns renders it especially vulnerable to glitches that initiate seizures. (Most epileptic seizures in adults begin in or near the hippocampus, Soltesz notes.)
agenangka In the study, Soltesz and his associates monitored split-second changes in levels of 2-AG in the hippocampus of mice during periods of normal activity, like walking or running, and in experiments in which brief seizures were induced in the hippocampus.
Agen Bandar Togel Online Terpercaya 2-AG is an endocannabinoid, a member of a family of short-lived signaling substances that are the brain’s internal versions of the psychoactive chemicals in marijuana. 2-AG and these plant-derived psychoactive chemicals share an affinity for a receptor, known as CB1, that’s extremely abundant on the surface of neurons throughout the brain.
agenangka “There have been lots of studies providing evidence for a connection between seizures and endocannabinoids,” Soltesz says. “What sets our study apart is that we could watch endocannabinoid production and action unfold in, basically, real time.”
